eBook: Metabolomics for NASH R&D

A clear path forward

Over the next decade, health experts expect Non-alcoholic steatohepatitis (NASH) to become the leading cause of liver transplants. Currently, there are no FDA-approved treatments for NASH. A diverse set of disease drivers including genetics, environmental cues, microbiota metabolism, and lifestyle influences come together resulting in an uncertain natural history of Non-alcoholic fatty liver disease (NAFLD) and NASH.

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The constellation of risk factors for NASH has spawned a remarkable array of targets, and there is a significant need to bring the most effective treatments through development and to patients quickly. Metabolomics provides a comprehensive picture of the metabolome and maps metabolites to their key biochemical pathways.

In this free, comprehensive eBook eBook, we discuss Metabolon’s Precision Metabolomics technology - a mass spectrometry-based method that allows for the identification of over 1000 small molecule compounds in a single sample and is suited for the many stages of drug development from target discovery, target engagement, safety and biomarker identification.